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1

Discovery of (2 S ,3 R )- N -[2-(Pyridin-3-ylmethyl)-1-azabicyclo[2.2.2]oct-3-yl]benzo[ b ]furan-2-carboxamide (TC-5619), a Selective α7 Nicotinic Acetylcholine Receptor Agonist, for the Treatment of Cognitive Disorders

Mazurov, Anatoly A., Kombo, David C., Hauser, Terry A., Miao, Lan, Dull, Gary, Genus, John F., Fedorov, Nikolai B., Benson, Lisa, Sidach, Serguei, Xiao, Yunde, Hammond, Philip S., James, John W., Mill

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 2.43 MB

english, 2012

2

Current rates and mechanisms of subsea permafrost degradation in the East Siberian Arctic Shelf

Shakhova, Natalia, Semiletov, Igor, Gustafsson, Orjan, Sergienko, Valentin, Lobkovsky, Leopold, Dudarev, Oleg, Tumskoy, Vladimir, Grigoriev, Michael, Mazurov, Alexey, Salyuk, Anatoly, Ananiev, Roman,

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 2.78 MB

english, 2017

3

Antiparasitic properties of leaf extracts derived from selected Nicotiana species and Nicotiana tabacum varieties

Schorderet Weber, Sandra, Kaminski, Kacper P., Perret, Jean-Luc, Leroy, Patrice, Mazurov, Anatoly, Peitsch, Manuel C., Ivanov, Nikolai V., Hoeng, Julia

Journal:

Food and Chemical Toxicology

Year:

2019

Language:

english

File:

PDF, 1.26 MB

english, 2019

4

2-(Arylmethyl)-3-substituted quinuclidines as selective α7 nicotinic receptor ligands

Anatoly Mazurov, Jozef Klucik, Lan Miao, Teresa Y. Phillips, Angela Seamans, Jeffrey D. Schmitt, Terry A. Hauser, Raymond T. Johnson Jr., Craig Miller

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 119 KB

english, 2005

5

Solid phase synthesis of 5,6,7,8-tetrahydro-1H-imidazo[4,5-g]quinoxalin-6-ones

Anatoly Mazurov

Journal:

Tetrahedron Letters

Year:

2000

Language:

english

File:

PDF, 85 KB

english, 2000

6

Traceless synthesis of benzimidazoles on solid support

Anatoly Mazurov

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 115 KB

english, 2000

7

TRH mimetics: Differentiation of antiamnesic potency from antidepressant effect

Anatoly A. Mazurov, Sergei A. Andronati, Tamara I. Korotenko, Nikolai I. Sokolenko, Alexei I. Dyadenko, Yury E. Shapiro, Vitalii Ya. Gorbatyuk, Tatyana A. Voronina

Journal:

Bioorganic & Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 1.00 MB

english, 1997

8

Design of a novel cognitive enhancer (8S, 10aS)-8-carbamoyl-1,2,3,6,7,8,9,10a-octahydro-5H,10H-pyrrolo[1,2-a][1,4]diazocin-5,10-dione

Anatoly A. Mazurov, Sergei A. Andronati, Tamara I. Korotenko, Nikolai I. Sokolenko, Alexei I. Dyadenko, Yuri E. Shapiro, Vitalii Ya. Gorbatyuk, Tatyana A. Voronina

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 293 KB

english, 1996

9

Discovery of 3-(5-Chloro-2-furoyl)-3,7-diazabicyclo[3.3.0]octane (TC-6683, AZD1446), a Novel Highly Selective α4β2 Nicotinic Acetylcholine Receptor Agonist for the Treatment of Cognitive Disorders

Mazurov, Anatoly A., Miao, Lan, Bhatti, Balwinder S., Strachan, Jon-Paul, Akireddy, Srinivasa, Murthy, Srinivasa, Kombo, David, Xiao, Yun-de, Hammond, Philip, Zhang, Jenny, Hauser, Terry A., Jordan, K

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 3.25 MB

english, 2012

10

Discovery of novel α7 nicotinic acetylcholine receptor ligands via pharmacophoric and docking studies of benzylidene anabaseine analogs

David C. Kombo, Anatoly A. Mazurov, Joseph Chewning, Philip S. Hammond, Kartik Tallapragada, Terry A. Hauser, Jason Speake, Daniel Yohannes, William S. Caldwell

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 1.33 MB

english, 2012

11

Docking studies of benzylidene anabaseine interactions with α7 nicotinic acetylcholine receptor (nAChR) and acetylcholine binding proteins (AChBPs): Application to the design of related α7 selective ligands

David C. Kombo, Anatoly Mazurov, Kartik Tallapragada, Philip S. Hammond, Joseph Chewning, Terry A. Hauser, Montserrat Vasquez-Valdivieso, Daniel Yohannes, Todd T. Talley, Palmer Taylor, William S. Cal

Journal:

European Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 1.40 MB

english, 2011

12

Deficiency of P-selectin in a patient with grey platelet syndrome

Alexey V. Mazurov, Dimitry V. Vinogradov, Svetlana G. Khaspekova, Anatoly V. Krushinsky, Ludmila V. Gerdeva, Sergei A. Vasiliev

Journal:

European Journal of Haematology

Year:

1996

Language:

english

File:

PDF, 426 KB

english, 1996

13

Formation of pyroglutamylglutamine (or asparagine) diketopiperazine in ‘non-classical’ conditions: a side reaction in peptide synthesis

ANATOLY A. MAZUROV, SERGEI A. ANDRONATI, TAMARA I. KOROTENKO, VITALY YA. GORBATYUK, YURY E. SHAPIRO

Journal:

Chemical Biology & Drug Design

Year:

1993

Language:

english

File:

PDF, 511 KB

english, 1993

14

Organic inclusions in salt. Part 3. Oil and gas inclusions in Cambrian evaporite deposit from East Siberia. A contribution to the understanding of nitrogen generation in evaporites

Svetlana Grishina, Jacques Pironon, Mikhail Mazurov, Sergey Goryainov, Anatoly Pustilnikov, German Fon-Der-Flaas, Alain Guerci

Journal:

Organic Geochemistry

Year:

1998

Language:

english

File:

PDF, 844 KB

english, 1998

15

Multiple Interaction Regions in the Orthosteric Ligand Binding Domain of the α7 Neuronal Nicotinic Acetylcholine Receptor

Xiao, Yunde, Hammond, Philip S., Mazurov, Anatoly A., Yohannes, Daniel

Journal:

Journal of Chemical Information and Modeling

Year:

2012

Language:

english

File:

PDF, 1.56 MB

english, 2012

16

3D Molecular Descriptors Important for Clinical Success

Kombo, David C., Tallapragada, Kartik, Jain, Rachit, Chewning, Joseph, Mazurov, Anatoly A., Speake, Jason D., Hauser, Terry A., Toler, Steve

Journal:

Journal of Chemical Information and Modeling

Year:

2013

Language:

english

File:

PDF, 2.12 MB

english, 2013

17

Analgesic effects mediated by neuronal nicotinic acetylcholine receptor agonists: Correlation with desensitization of α4β2* receptors

Zhang, Jiahui, Xiao, Yun-De, Jordan, Kristen G., Hammond, Phil S., Van Dyke, Katherine M., Mazurov, Anatoly A., Speake, Jason D., Lippiello, Patrick M., James, John W., Letchworth, Sharon R., Bencheri

Journal:

European Journal of Pharmaceutical Sciences

Year:

2012

Language:

english

File:

PDF, 672 KB

english, 2012

18

Novel nicotinic acetylcholine receptor agonists containing carbonyl moiety as a hydrogen bond acceptor

Mazurov, Anatoly A., Kombo, David C., Akireddy, Srinivasa, Murthy, Srinivasa, Hauser, Terry A., Jordan, Kristen G., Gatto, Gregory J., Yohannes, Daniel

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 1.98 MB

english, 2013

19

Discovery and Development of α7 Nicotinic Acetylcholine Receptor Modulators

Mazurov, Anatoly A., Speake, Jason D., Yohannes, Daniel

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 2.08 MB

english, 2011

20

Computational studies of novel carbonyl-containing diazabicyclic ligands interacting with α4β2 nicotinic acetylcholine receptor (nAChR) reveal alternative binding modes

Kombo, David C., Mazurov, Anatoly A., Strachan, Jon-Paul, Bencherif, Merouane

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 3.02 MB

english, 2013

21

The effects of changes in testosterone level on the development of metabolic syndrome

Pechersky, Alexander, Semiglazov, Alexander, Loran, Oleg, Mazurov, Vadim, Karpischenko, Anatoly, Nikiforov, Aleksy, Kalinina, Natalya, Drygina, Laryssa, Davydova, Natalya, Skorobogatikh, Marina

Journal:

Gender Medicine

Year:

2006

Language:

english

File:

PDF, 123 KB

english, 2006

22

Identification and pharmacological characterization of 3,6-diazabicyclo[3.1.1]heptane-3-carboxamides as novel ligands for the α4β2 and α6/α3β2β3 nicotinic acetylcholine receptors (nAChRs)

Strachan, Jon-Paul, Kombo, David C., Mazurov, Anatoly, Heemstra, Ronald, Bhatti, Balwinder S., Akireddy, Rao, Murthy, Srinivasa, Miao, Lan, Jett, John E., Speake, Jason, Bencherif, Merouane

Journal:

European Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 2.05 MB

english, 2014

23

Selective α7 Nicotinic Acetylcholine Receptor Ligands

Mazurov, Anatoly, Hauser, Terry, Miller, Craig

Journal:

Current Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 634 KB

english, 2006

24

Erratum

Kem, William, Mazurov, Anatoli

Journal:

Current Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 19 KB

english, 2007

25

Pharmacological Characterization of Natural Tobacco Alkaloids in the Presence of Positive Allosteric Modulators Against Human Î±4Î²2 and Î±7 Nicotinic Acetylcholine Receptors

Alijevic, Omar, Mc Hugh, Damian, Mazurov, Anatoly, Hoeng, Julia, Peitsch, Manuel

Journal:

Biophysical Journal

Year:

2020

File:

PDF, 46 KB

2020